Postdoc Position in Onco-ImmunoMetabolism

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A Postdoctoral position, funded by the Italian Association for Cancer Research (AIRC, Associazione Italiana per la Ricerca sul Cancro), is available to join the newly-established Cancer Metabolism Laboratory led by Dr. Simone Cardaci at the San Raffaele Scientific Institute in Milan (Italy).

The funded project aims at generating mechanistic understanding of the metabolic reprogramming of cancer, identifying metabolic vulnerabilities in tumours and determining how the metabolic landscape of the tumour microenvironment affects anti-tumour immune responses. These objectives will be achieved by employing metabolomics, functional genomics and flow cytometryintegrated approaches in chemically-induced and genetic mouse models of cancer.

You will have successfully completed a PhD in immunology (or a field relevant to the immunobiology of cancer) and have research experience in tumour immunology and/or immunometabolism, proven by good first-author publications record in recognized journals.

The position requires hands-on experience with multicolour flow-cytometry, aseptic cell culture techniques and mouse models of cancer. Skills in gene editing technology (CRISPR/Cas9), molecular cloning and microscopy would be highly helpful. English fluency and computer literacy are a must. Importantly, you are expected to be a self-motivated researcher committed to developing your academic career in cancer research, driven by scientific curiosity, with good ability to work independently and be proactive in developing personal line of research on the topic of the group.

Research activity will be based at the Division of Genetics and Cell Biology within the San Raffaele Scientific Institute, a forefront multidisciplinary biomedical research campus in Italy ( You will benefit from a dynamic and collaborative research environment, access to state of-the-art research facilities ( and a competitive salary, commensurate to qualifications and experience (initial 2 year fixed term contract, with possibility of extension up to 5 years).

Please send a full CV, brief motivation letter, a statement on your past research experience and future research goals as well as contact details for three referees to Dr. Simone Cardaci (

Interviews of shortlisted candidates will take place from March 2018 until the position is filled.

KEY REFERENCES: Sciacovelli et al, Nature (2016); Rizza et al, Cancer Res (2016); Cardaci et al, Nat. Cell Biol. (2015); Zheng, Cardaci et al, Nat. Commun (2015); Cardaci et al, Autophagy (2012); Cardaci et al, Cancer Res (2012); Cardaci et al, J. Cell Sci (2012).


IMMUTRAIN- Immunotherapy of Cancer - 15 positions as PhD students

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European Innovative Training Network IMMUTRAIN

15 positions as Early Stage Researcher (PhD student) in the field of Immunotherapy of Cancer

Description: IMMUTRAIN is a research network funded by the Marie Skłodowska-Curie Actions. It comprises nine academic research groups and five industrial partners in nine European countries. The joint goal is to train the next generation of scientists in the field of immunotherapy of cancer. The research objective of IMMUTRAIN is to enhance the efficacy of antibody-based tumor therapies through combination with other immunotherapeutic approaches. Please find further information at

We offer: Cutting edge research projects and training with leading experts in the field of immunotherapy of cancer; employment contract for three years with the benefits of the EU Marie Skłodowska-Curie programme; opportunities for future employment.

We seek: Excellent scientists with a master degree or equivalent in natural sciences or related disciplines (such as medicine or pharmacy); practical skills in modern laboratory work, preferentially combined with experience in animal experiments.

Your profile: You must be within your first four years of research experience after completion of your masters degree or equivalent; you cannot hold a doctoral degree at the time of recruitment; you cannot have spent more than 12 months within the past 36 months in the country where the position you are applying for is located (mobility rule); you must be proficient in the English language both written and spoken (proof required).

Open positions:
- WP1, Combination of antibodies with adoptive T cell transfer: ESR 1 and ESR 2 (Ludwig-Maximilians-Universität, Germany), ESR 3 (Nottingham Trent University, UK), ESR 4 and ESR 5 (University Hospital Herlev, Region Hovedstaden, Denmark)
- WP2, New formulations of antibodies to activate immune cells: ESR 6 (Ludwig- Maximilians-Universität, Germany), ESR 7 (Roche Diagnostics GmbH, Germany), ESR 8 (Istituto Europeo di Oncologia, Italy)
- WP3, Combination of antibodies with dendritic cell therapy: ESR 9 (Radboud University Medical Centre, Netherlands), ESR 10 (Medical University of Innsbruck, Austria)
- WP4, Combination of antibodies with therapeutic nucleid acids: ESR 11 (Institut Gustave Roussy, France), ESR 12 (Université de Fribourg, Switzerland), ESR 13 (Ludwig- Maximilians Universität München, Germany), ESR 14 and ESR 15 (Spanish National Cancer Research Center, Spain)

The application procedure will be carried out in compliance with the Code of Conduct for Recruitment and the Charter for Researchers. Please send your application until Friday March 4th, 2016 to: We look forward to your application.


Research fellowship in Tumor Immunology at the San Raffaele Institute in Milano, Italy.
Educating T cells against cancer.

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A fellowship is immediately available at the San Raffaele Scientific Institute in Milan, Italy within the Lymphocyte Activation Unit, Division of Immunology. Applications from both pre- and post-doctoral candidates with a strong motivation for research and a deep interest in immunology will be considered. Salary will be commensurate to previous experience. The project is based on a combined adoptive/active immunotherapy approach developed in the lab (Hess Michelini, Cancer Res. 2010; Manzo J. Immunol 2011; Hess Michelini, Cancer Res. 2013) and is centered on the use of TCR-redirected T cells for the immunotherapy of solid tumors. The fellow will work with mouse models of cancer and adopt cell-intrinsic and cell-extrinsic means to promote intratumoral recruitment and reactivation of engineered T cells. The fellow will benefit of the collaborative environment of an Immunology, BioImmunotherapy and Gene Therapy of Cancer Network, of PhD and postdoc training activities, and Institutional lectures and seminars. Facilities (animal housing, flow cytometry, imaging) will be available along with technical support. Previous experience on viralmediated T cell transduction, animal handling, flow cytometry and molecular biology along with an established publication record will provide a selective advantage.

Interested candidates should send a CV, statement of interest, and two reference contacts to Anna Mondino at For additional info visit: diseases/anna-mondino/

Applications will be competitively considered and the position promptly assigned. A one-year renewable position will be offered.